Another major breakthrough
was reported in the search for a
cure for AIDS.
After bone marrow
transplantation, two HIV-
infected men have no longer
any trace of the virus that
causes AIDS in their cells,
researchers report.
Lymphocytes are a type of white
blood cells and are a key part of
the immune
system.
U.S. investigators suspect that
the bone marrow transplant,
together with the
continuation of antiretroviral
therapy as a result of the
dramatic effects evident eight
months after transplantation.
They are
scheduled to present
preliminary findings
Thursday at the International
AIDS Conference in
Washington, DC.
HIV patients receiving
antiretroviral therapy often get
"an undetectable viral
load" meaning no virus particles
in their blood. But they still have
latent HIV in
their cells, and if
antiretroviral therapy was
stopped, it could reactivate
latent HIV.
Because they had no traces of
HIV in their white blood cells is
an indication that the
"pool" of latent HIV may have
been eliminated, the
researchers believe.
At this point, researchers are
far from saying these
patients are cured.
However,
the findings are "exciting,"
said Dr. Savita Pahwa,
director of the Center for AIDS
Research at the University of
Miami Miller
School of Medicine, who was
not involved in the study.
"Each clue that is obtained that
it is possible to eliminate
latent HIV must be
investigated," she said.
"The elimination of the reserve
HIV is the key to a cure," said
Pahwa. She stressed it would
only be possible to say that
these patients were
"functionally
cured" if the virus will not
reactivate when the patients
were off antiretroviral therapy.
Sunday, 24 February 2013
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